Cuba is a city in Crawford County, Missouri, United States. The population was 3,356 at the 2010 census. Cuba is the largest city situated entire…Cuba is a city in Crawford County, Missouri, United States. The population was 3,356 at the 2010 census. Cuba is the largest city situated entirely in Crawford County. Cuba was platted in 1857 when it was certain the railroad would be extended to that point. It was named after the island of Cuba.
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