There was also an increase in the number of stem-like memory T cells, which are able to perform either effector or memory functions if they encounter a pathogen again. Effector cells are involved in ...

C ytotoxic T cells are an important component of the immune system. Once activated, they differentiate into either short-lived effector cells or long-lived memory cells. Studies by researchers at ...

Upon initial activation by their cognate antigen, naïve CD8 + T cells start to proliferate and differentiate into short-lived effector and long-lived memory precursor cells. How a single ...

Although effector activity and memory formation in CD8 + T cells are known to depend on mTORC1-mediated metabolic regulation, the molecular mechanisms involved are lesser known. Here authors ...

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way ...

OX40R is a co-stimulatory molecule expressed on activated effector and memory T cells, and OX40R-positive T cells release pro-inflammatory cytokines that drive memory responses in AD. The number ...

We are interested in further understanding the molecular and cellular mechanisms involved in NK cell development, effector function, and generation of memory. We have recently demonstrated that ...

Vaccine-induced T cells transitioned from proliferative to effector states and stabilized as tissue-resident memory-like (TRM-like) cells, retaining cytotoxic functions for years. Persistent CD8 ...

During a parasitic infection, specific immune cells, known as virtual memory T cells (T VM), become activated and express a surface molecule called CD22, which prevents an excessive immune reaction.