The Knicks were missing their KAT, while the 76ers were without a much larger portion of their litter. With Karl-Anthony Towns sidelined with a sprained right thumb — and as The Post first reported, also a bone chip in the same digit — the Knicks flushed a 16-point first-half lead before barely pulling out a 125-119 overtime win Wednesday night over the Sixers at Wells Fargo Center.

Though New York Knicks star Karl-Anthony Towns’ thumb injury is worse than initially thought, he’s not expected to miss much time at all. Towns went down with a thumb sprain in the team’s loss to the Detroit Pistons on Monday.

Philadelphia will try to stop its three-game losing streak when the Philadelphia 76ers play New York. The teams square off Wednesday for the first time this season.

Though New York Knicks star Karl-Anthony Towns’ thumb injury is worse ... which dropped to 15-24 with the loss, and Kelly Oubre Jr. finished with 16 points and 10 rebounds.

Simons and Ayton lead the way, with Simons dropping 24 on 6-12 three-point shooting, adding four boards, and three assists. Ayton posted a double-double putting up 22 points, and pulling down 15 rebounds. Avdija also added a double-double, scoring 16 with 10 rebounds.

PHILADELPHIA (AP) — Jalen Brunson scored 16 of his 38 points in the fourth quarter and overtime, and Josh Hart had the 11th triple-double of his career as the New York Knicks beat the Philadelphia 76ers 125-119 on Wednesday night.

In the second half, the Sixers showed signs of the team they were supposed to be without Joel Embiid. But their dreadful first half sunk them to 15-24.

Here are the biggest takeaways for the short-handed Philadelphia 76ers following a tough overtime loss to the New York Knicks.

Despite a good game from Paul George and a huge second half from Tyrese Maxey, the Sixers dropped their fourth straight game.

The National Basketball Association (NBA) has five games on the schedule, with a doubleheader on TNT/truTV/Max. The New York Knicks and Brooklyn Nets tip off at 7:30 p.m. ET at Barclays Center in the front end

Mark Williams scored a career high 31 points and had 13 rebounds to help the Charlotte Hornets beat the Utah Jazz 117-112 on Wednesday night. LaMelo Ball added 27 points, nine assists and three blocks to help Charlotte snap a seven-game road losing streak.

Brunson scored 38 points and took control in overtime, while Hart recorded a triple-double and Bridges scored 23 points in the city where they became college stars.