The authors have generated important resources such as a reference dataset of early primate development by utilizing single-cell transcriptomic technology together with induced pluripotent stem cells ...

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Oncogene permanent activation in a single targeted cell of zebrafish together with a reprogramming factor transient activation is sufficient to induce the malignant transformation of the cell and ...

Researchers at the University of Tsukuba have developed a vector that integrates the Cre enzyme gene with the specific DNA ...

Gene expression ... determines cell fate and phenotypic variability, but its molecular mechanisms are not well understood. Here the authors present a high-resolution single-cell yeast ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene ... PROX1 acts as a molecular ‘cell fate guardian’ in hepatocytes, preserving liver cell ...

Vertex Pharma's £1.65 million ($2.05 million) gene-editing therapy for sickle cell disease (SCD), Casgevy, has been given the green light for use by the NHS in England under a managed access ...

10, 2024 — In a single ... how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated ... Noninvasive Measurement of Gene Expression at Target ...

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