The goals of a Phase 2 clinical trial are to determine if the treatment is effective and to gather more safety data. Researchers use the data from Phase 2 trials to refine their research questions ...

Clinical trials start with Phase I to assess drug safety in a small group. Phase II tests effectiveness and side effects on a larger group. Phase III compares the new drug to existing treatments ...

Even after a successful preclinical phase, a drug could fail to clear clinical trials, for instance because animal models may not accurately mimic disease processes in humans. 11 Incomplete knowledge ...

Phase III trials. These trials have anywhere from 100 to thousands of people, and they compare a drug to the standard treatment. Scientists may test a new drug or a new use for an approved ...

The Case Comprehensive Cancer Center (Case CCC) has budgeted funds for the conduct of early phase clinical trials of relatively short duration. The objectives are to identify and fund ...

Recently, alternative endpoints, including progression-free survival (PFS), have emerged as popular readouts for many phase 3 clinical trials. PFS indicates the time from diagnosis (or treatment ...

Our courses, including the sought-after PG Diploma in Clinical Research, ensure that our students are well-prepared to drive the complex terrain of clinical trials. In this article, we will decode the ...

Ascletis Pharma Inc. (HKEX: 1672, "Ascletis") announces today that denifanstat (ASC40), a first-in-class, once-daily oral small molecule fatty acid synthase (FASN) inhibitor, meets all primary ...

Another Phase III Trial Failure in Neuroscience: ... the failure of late-stage clinical trials in neurology is an all-too-familiar tale. ... The definition of the disease, ...

YANTAI, China, April 8, 2025 /PRNewswire/ -- On April 8, 2025 (UTC-7), impressive results of the Phase 3 clinical trial (NCT05737160) evaluating the efficacy and safety of Telitacicept (synonym ...

The goals of a Phase 2 clinical trial are to determine if the treatment is effective and to gather more safety data. Researchers use the data from Phase 2 trials to refine their research questions ...