Vakoc suggested that his lab developed a new technology to find cancer targets, enabling them to search for processes and ...

It has long been understood that the Hippo pathway plays a critical role in the development of a wide range of diseases. Although once seen as an elusive pathway, emerging novel data and research ...

The genes that handle weight in fruit flies have corresponding genes in humans. That’s where the Hippo pathway comes in. The Cambridge researchers first searched for obesity genes in humans ...

Since only a few PI5P4K regulators were known, the research team screened 29 other potential regulators and found two—core ...

Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...

The Hippo pathway has been delineated during the past four years (for recent reviews, see refs 3–5).Although primarily worked out in Drosophila, homologues of the pathway components exist in ...

The lab reported in the journal Science that a gene pathway called Hippo inhibits cardiac muscle regeneration during development. View the Science Journal article. Our lab is currently working to ...