Mortality rates from Ebola outbreaks can be as high as 90%, according to the Centers for Disease Control and Prevention, and ...
Vakoc suggested that his lab developed a new technology to find cancer targets, enabling them to search for processes and ...
It has long been understood that the Hippo pathway plays a critical role in the development of a wide range of diseases. Although once seen as an elusive pathway, emerging novel data and research ...
The genes that handle weight in fruit flies have corresponding genes in humans. That’s where the Hippo pathway comes in. The Cambridge researchers first searched for obesity genes in humans ...
The Hippo pathway has been delineated during the past four years (for recent reviews, see refs 3–5).Although primarily worked out in Drosophila, homologues of the pathway components exist in ...
Among these signals, the TGF-β and HIPPO pathways are critical, functioning as tumor suppressors and regulating liver development and regeneration. The review focuses on these pathways' interplay ...
The expansion of the Salvador (SAV)–Warts (WTS)–Hippo (HPO) pathway continues with three recent papers that extend the list of upstream regulators and identify links to Wnt signalling.
This interesting study presents valuable information on how human cytomegalovirus (HCMV) infection disrupts the activity of the TEAD1 transcription factor, leading to widespread chromatin alterations.