Giamundo et al. present fundamental data with new insights into the role of Ezrin, a major membrane-actin linker that assembles signaling complexes, in the spatial regulation of EGF signaling ...
Mice with tuberous sclerosis complex 1 (TSC1) or Rheb deletion specifically in the myeloid lineage were generated and subjected to intra-articular injection of collagenase (collagenase-induced ...
Results: We demonstrated that the specific pathway-related molecules (SMARCA4, MLH1, TSC1, ATRX, and ATR) were associated with cytolytic activity. Then we identified the two distinct patterns of ...
TSC1-related, pig (MONDO:1012894) multifocal symmetrical necrotizing encephalomyelopathy, Simmental cattle (MONDO:1012698) von Willebrand disease II, horse (MONDO:1012668) Y anomaly in low ...
2012). Accordingly, mice with constitutive mTORC1 activation in adipocytes induced by tuberous sclerosis complex (TSC1) deletion in differentiated, mature adipocytes significantly reduces visceral ...
For the seventh year in a row, St. Catherine University accomplished a 100% acceptance rate for undergraduate student presentations submitted to the National Conference for Undergraduate Research ...
Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...
Background Lymphangioleiomyomatosis (LAM) is a rare multisystem disease almost exclusively affecting women which causes loss of lung function, lymphatic abnormalities and angiomyolipomas. LAM occurs ...
Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...
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