The U.S. economy has never been more integrated with Canada and Mexico. The 25% tariffs that President Trump has said he would impose on America’s two largest trading partners on Tuesday could upend those relationships—and no sector is as exposed as the automotive industry.

Canada and Mexico on Friday sought to show U.S. President Donald Trump's administration evidence of progress in curbing the flow of fentanyl opioids into the U.S. ahead of a March 4 deadline for punishing 25% tariffs on their goods imports.

Mexican President Claudia Sheinbaum says she hopes to speak with U.S. President Donald Trump now that he has announced plans to impose tariffs on Mexico and Canada starting Tuesday.