Ever since making the switch from high school receiver to running back in college, Isaac Guerendo has had few opportunities ...

Running back Christian McCaffrey is on injured reserve for the second time this season, but San Francisco 49ers coach Kyle ...

Christian McCaffrey's injury-ridden season took another unfortunate turn when the star running back went down with another ...

Christian McCaffrey practiced little and played less this season, seeing action in four games with 65 touches. He is out for the season with his knee injury that will require a six-week recovery.

McCaffrey immediately checked himself out of the game and ran right into the medical tent. The 49ers star RB missed the ...

San Francisco 49ers running back Christian McCaffrey reflected on his 2024 NFL season that fell short of expectations with a ...

Christian McCaffrey suffered a PCL injury in the 49ers' Week 13 loss to the Bills. He addressed the injury on social media ...

San Francisco 49ers running back Christian McCaffrey made his season debut less than one month ... shared his initial ...

Isaac Guerendo will make his first NFL start on Sunday as the injury-depleted San Francisco 49ers face the Chicago Bears. The ...

Slow motion video shows where 49ers running back Christian McCaffrey seemingly injured himself and ended his season.

McCaffrey should be fine long term, though it's hard to say whether he'd be able to play again this season if the 49ers made ...

The San Francisco 49ers are falling behind the Seattle Seahawks in the NFC West. Losers of three consecutive contests, it was ...