Most of the clinical trials reported on this website are phase III trials. Pre-clinical research screens or synthesises possible drugs or vaccines, ... Trials of prevention methods such as vaccines or ...

The pivotal trial for Neurogene's Rett syndrome gene therapy makes use of baseline controls and a rigorous endpoint that ...

Because of the multifocal nature of urothelial tumors, this definition excluded new or recurrent tumors of the urethra, bladder, ureters, ... Multicenter Phase II Clinical Trial of Gemcitabine and ...

Another Phase III Trial Failure in Neuroscience: ... the failure of late-stage clinical trials in neurology is an all-too-familiar tale. ... The definition of the disease, ...

An ongoing phase 3 study of the efficacy, safety, and immunogenicity of candidate malaria vaccine RTS,S/AS01 is being conducted in seven African countries.From March 2009 through January 2011, we e ...

The use of novel brain biomarkers using nuclear magnetic resonance imaging holds potential of making central nervous system (CNS) drug development more efficient. By evaluating changes in brain ...

Missing data have seriously compromised inferences from clinical trials. 1 For example, editorials in the Journal have noted how missing data have limited the ability to draw definitive ...