At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

The role of tumor-infiltrating immune cells in the early metastatic invasion of colorectal cancer is unknown. We studied pathological signs of early metastatic invasion (venous emboli and lymphatic ...

Models of the pathways of effector and memory T-cell differentiation are discussed, and we highlight the implications of this new understanding for the optimization of vaccine strategies.

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

It highlights the differentiation of various T cell subsets, including conventional naïve T cells, regulatory T cells, effector T cells, and memory subsets, as well as unique subsets like γδ T ...

Once activation upon encountering antigens, naïve CD8 T cells undergo a rapidly proliferative expansion and differentiate into effector and memory cells, which enhance the protection of organisms ...

Aging is known to be a risk factor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells ...

Engineered regulatory T cells were able to calm the gluten-reactive effector T cells that cause the autoimmune response seen in celiac disease.

They found that the FcRL5+ T-bet+ hemagglutinin-specific memory B cells were transcriptionally similar to effector-like memory cells, while the FcRL5neg T-betneg hemagglutinin-specific memory B cells ...

Months after announcing an M&A deal with AstraZeneca, EsoBiotec has released the first small slice of data on the cell ...

Researchers introduce a chimeric antigen receptor–enhancer (CAR-E) therapeutic platform that significantly extends the effectiveness and memory of CAR T cells, potentially preventing relapse in ...