Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Dr Dinesh Pendharkar highlights how CAR T–cell therapy is reshaping cancer care in India by equipping the immune system with ...

A research team led by The University of Osaka finds that elevated levels of certain immune cells in patients with systemic ...

The healthy brain hosts very few T cells. However, they can be summoned to the brain when threats arise. This seems to be the case in people with AD or PD, whose CSF and brain tissue swarm with CD8+ T ...

imageimageCD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute infection. Tet1/3 thus act as determinants of CD8 T cell fates by ...

Engineered regulatory T cells were able to calm the gluten-reactive effector T cells that cause the autoimmune response seen in celiac disease.

Researchers introduce a chimeric antigen receptor–enhancer (CAR-E) therapeutic platform that significantly extends the effectiveness and memory of CAR T cells, potentially preventing relapse in ...