Models of the pathways of effector and memory T-cell differentiation are discussed, and we highlight the implications of this new understanding for the optimization of vaccine strategies.

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

To this end, a subset of effector memory T-cell-like CD8+ T-cells that are persistently present in airway mucosa were identified.

image: During viral infection, total m 6 A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T cell expansion ...

It highlights the differentiation of various T cell subsets, including conventional naïve T cells, regulatory T cells, effector T cells, and memory subsets, as well as unique subsets like γδ T ...

"It generated not only effector T cells, which most patients already have, but also stem cell–like memory T cells, central memory T cells, effector memory T cells—a complete repertoire of the ...

They found that CD8 T cells that accumulate in atherosclerotic plaques in aging mice are primarily memory T cells, both effector memory T cells and central memory T cells, ...

However, they can be summoned to the brain when threats arise. This seems to be the case in people with AD or PD, whose CSF and brain tissue swarm with CD8+ T effector memory cells (Jan 2020 news).

When broken-down bits of gluten are presented on the DQ2.5 variant of HLA, effector T cells react aggressively and cause celiac disease symptoms.