The Mass General Brigham Gene and Cell Therapy Institute, a hub of innovation dedicated to accelerating groundbreaking research, conducting clinical trials and developing FDA-approved treatments, ...

Using STC-1 cell line and different mouse models, including Neurog3-Tsc1−/− mice, rapamycin or L-lucine treatment to stimulate mTOR activity, we have demonstrated that mTOR stimulates proglucagon gene ...

Differentiating hereditary from nonhereditary retinoblastoma is now possible overnight, improving early intervention ...

On the basis of personal and family history as well as patient preference, the majority of patients underwent Common Hereditary Cancers gene panel testing (47 genes—done at Invitae Genetics Laboratory ...

Nov. 22, 2024 — Geneticists have developed a gene drive-based solution to the widespread problem of insecticide resistance. In an effort to protect valuable crops, the researchers created an 'e ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

CRISPR/Cas9 is a gene editing tool that has revolutionized biomedical research and led to the first FDA-approved CRISPR-based gene therapy. However, until now, the precise mechanism of exactly how ...

Gene Park is a reporter for The Washington Post, covering video games and gaming culture. He joined The Post in 2015 as audience editor, and is a former reporter in the West Coast and Pacific region.

Diagnostic hypothesis of TSC2/PKD1 Contiguous Gene Syndrome was placed, which was confirmed by the genetic testing. At 13 years of age, patient continued to be seizure free; she had normal cognitive ...

Epilepsy is very common in tuberous sclerosis complex and occurs in 80 to 90% of affected individuals during their lifetime. Onset usually occurs during childhood, and up to one third of children ...