The third-generation aromatase inhibitors provide novel approaches to the endocrine treatment of breast cancer. These drugs are effectively challenging tamoxifen, the previous gold standard of ...

Dr. Alicia Arnold and Dr. Priyanka Raval discuss first- and later-line treatment options for those with ER-positive, ...

Treatment with an aromatase inhibitor for 5 years as up-front monotherapy or after tamoxifen therapy is the treatment of choice for hormone-receptor–positive early breast cancer in ...

Aromatase inhibitors act through pure oestrogen deprivation to achieve an endocrine response in oestrogen receptor (ER)-positive breast cancer. Both experimental and clinical data now confirm that ...

Aromatase inhibitors (AIs), like arimidex, aromasin and femara, are also used to help fight cancer cell regrowth. These drugs work to block cell receptors like estrogen and progesterone in breast ...

Aromatase inhibitors for breast cancer: Advantages over tamoxifen in early-stage disease Longer survival, later recurrences/ Evidence for late-stage disease much poorer ...

Aromatase inhibitors were just as effective in women aged under 35, who have a higher risk of recurrence than older women. There was no apparent difference in the number of deaths from breast ...

A number of adjuvant breast cancer trials are currently evaluating all 3 third-generation aromatase inhibitors relative to the current standard, tamoxifen for 5 years. In comparing efficacy and ...

Aromatase inhibitors are not appropriate for premenopausal patients for a number of reasons. First, higher circulating levels of androgens present in premenopausal women compete with aromatase ...

Aromatase inhibitors were originally developed for the treatment of estrogen-receptor-positive breast cancer, 1 and these drugs have been used in clinical trials for other conditions in children ...

I have been on an aromatase inhibitor for the past eight months and have side effects that keep me from having a good quality of life. I am supposed to be on it for five years, but I do not want ...

Aromatase inhibitors work to lower your levels of estrogen. These oral meds are usually taken once a day. They include the drugs letrozole (Femara), anastrozole (Arimidex), and exemestane (Aromasin).