Guerendo won't return to Sunday's game at Arizona due to knee and ankle injuries. Guerendo had his left leg twisted under him on his second carry of the game, and his teammates quickly motioned to the ...

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo ...

Jahmyr Gibbs and Isaac Guerendo will be the featured fantasy football running backs on Monday Night Football in Week 17.

Should I start or sit Isaac Guerendo for fantasy football in Week 17? Read our fantasy football start 'em, sit 'em picks and ...

San Francisco 49ers running back Isaac Guerendo exited early in the team’s Week 18 matchup vs. the Arizona Cardinals. What’s the latest on the Niners’ rookie running back? What Happened to Isaac ...

It isn't always easy finding the best player to put in your FLEX spots in fantasy football. While your other slots typically ...

SportsLine expert Jimmie Kaylor shares his Week 17 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...

The Week 17 edition of Monday Night Football may not mean much for either the San Francisco 49ers or Detroit Lions, but it means plenty for bettors and fantasy ...

Isaac Guerendo, RB, SF (foot/hamstring) — Expected to play In Guerendo’s Week 16 absence, Patrick Taylor had eight carries for 24 yards, while WR Deebo Samuel had five carries for 25 yards. But ...

The San Francisco 49ers running back is questionable with a sprained foot, but per ESPN’s Adam Schefter: he “plans to play” and Guerendo has said he feels good.