The 49ers' goal last offseason was to strengthen their depth in pursuit of another NFC crown. That depth has been tested and ...

Watch the best touchdowns from Week 13 of the 2024 NFL season. Watch all of Buffalo Bills running back James Cook's best ...

Daily Fantasy millionaire Mike McClure shares his top NFL DFS picks for Buffalo Bills vs. San Francisco 49ers on SNF ...

But now it is back to the drawing board, not only for McCaffrey, but the 49ers at large. His injury, of course, is just one ...

Injuries and missed opportunities have defined the San Francisco 49ers' 2024 season. Can they overcome setbacks and make a ...

Rather than viewing this team as one of the class organizations of the NFC, we now need to ponder whether injuries, age, and ...

San Francisco 49ers quarterback Brock Purdy feels sorry for the brutal injury suffered by Christian McCaffrey.

The San Francisco 49ers are in dire straights after a blowout loss to the Buffalo Bills, and QB Brock Purdy knows it.

Kirk Cousins threw four interceptions and tossed the Atlanta Falcons’ playoff plans into disarray. Brock Purdy couldn’t ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...