Isaac Guerendo, San Francisco 49ers

Latest update on Isaac Guerendo’s knee brings positive news for the 49ers ahead of the 2025 NFL season
The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be complete in time for the upcoming NFL season.
49ers RB Isaac Guerendo carted off with knee and ankle injuries
San Francisco running back Isaac Guerendo was injured and carted off early during the 49ers ‘ season finale versus the Arizona Cardinals.
49ers RB Isaac Guerendo shares positive injury update
San Francisco 49ers running back Isaac Guerendo was forced to exit Sunday's game against the Arizona Cardinals during the first offensive drive. He was
49ers’ Isaac Guerendo Suffers Injury in Season Finale vs. Cardinals
Unfortunately, San Francisco 49ers' running back Isaac Guerendo was carted off the field early in the first quarter.
Standout 49ers rookie delivers positive update after scary Week 18 injury
The 49ers lost their standout rookie Isaac Guerendo in scary fashion. What update did the running back provide Monday?
MRI reveals 49ers RB Isaac Guerendo suffered MCL, ankle sprains
San Francisco 49ers rookie RB Isaac Guerendo suffered MCL and ankle sprains against the Arizona Cardinals, avoiding an ACL injury.
49ers' Isaac Guerendo Says His 'ACL Is Good' After Being Carted Off with Injury
San Francisco 49ers running back Isaac Guerendo gave a positive update on his knee injury Monday, noting he did not tear his ACL as some had speculated:
49ers rookie may have avoided major injury in loss to Cardinals
San Francisco running back Isaac Guerendo exited the 49ers' season finale versus the Arizona Cardinals just four plays into the contest. On his second carry of the afternoon, Guerendo's left leg was twisted up and he had to be carted off.
49ers season ends mercifully in 47-24 loss to the Cardinals
The San Francisco 49ers came out of the gates aggressively against the Arizona Cardinals. Ricky Pearsall caught a 30-yard pass on the second play from scrimmage. Unfortunately, the Niners would lose rookie running back Isaac Guerendo to what appeared to be a severe knee injury.
San Francisco 49ers
Rookie running back Isaac Guerendo was carted off the field less than two minutes into the first quarter during the 49ers’ ...
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Isaac Guerendo injury update: San Francisco 49ers RB carted off field after scary tackle
San Francisco 49ers Isaac Guerendo was carted off the field Sunday against the Arizona Cardinals. He suffered the injury ...
49ers RB Isaac Guerendo 'good to go' vs. Lions
San Francisco 49ers running back Isaac Guerendo is set to return from foot and hamstring injuries and play Monday vs. the ...
49ers RB Isaac Guerendo Expected To Play vs Lions
While the Lions are preparing to make a deep run in the playoffs, the 49ers have lost their last two games and have dropped ...
49ers RB Carted Off Field vs Cardinals
GLENDALE -- San Francisco 49ers RB Isaac Guerendo was carted off the field in Week 18's matchup against the Arizona Cardinals. He has already been ruled out with a knee and ankle injury. On just the ...