Jun 26, 2024 · Clinical trials are a type of research that studies new tests and treatments and evaluates their effects on human health outcomes. People volunteer to take part in clinical trials to test medical interventions including drugs, cells and other biological products, surgical procedures, radiological procedures, devices, behavioural treatments and ...

Aug 10, 2021 · This means enrolling people from diverse geographic areas, racial and ethnic backgrounds, genders, and ages, as well as those with underlying health conditions that put them at higher risk for COVID-19. Including these groups in clinical trials is the only way to make sure that a vaccine will be safe and effective for everyone who needs it.

Dec 8, 2020 · If the vaccine triggers an immune response, it is then tested in human clinical trials in three phases. Phase 1. The vaccine is given to a small number of volunteers to assess its safety, confirm it generates an immune response, and determine the right dosage. Generally in this phase vaccines are tested in young, healthy adult volunteers. Phase 2

Strengthening research ecosystems: It advocates reforming national clinical research ecosystems, involving patients, the public, and communities to align research with public needs and sustain trust. Enhancing randomized controlled trials (RCTs) design and oversight: It emphasizes that RCTs should be ethical, efficient, and informative, using ...

Sep 25, 2024 · This guidance updates and adapts the previous work of the World Health Organization (WHO) on research capacity for the context of well-designed and well-implemented clinical trials as framed in resolution WHA75.8 (2022). It aims to enhance clinical research efficiency, minimize research waste and provide guidance on sustained clinical trials that are …

Jan 16, 2020 · The ICTRP is a country-led initiative. Clinical trial registration happens when countries seek to improve the transparency of clinical trial research involving nationals of that country, and to be more accountable to the individuals who consent to participate in clinical research, and to better oversee and monitor that research.

The number of trials listed in the WHO International Clinical Trials Registry Platform (ICTRP) is reported by year, location (WHO region and country), disease (or condition), phase of development, age, sex and number of participants. Note that the ICTRP comprises both interventional and observational trials. See more on the scope of the ICTRP ...

Mar 30, 2023 · Provides summary tables of COVID-19 vaccine candidates in both clinical and pre-clinical development; Provides analysis and visualization for several COVID-19 vaccine candidate categories; Tracks the progress of each vaccine from pre-clinical, Phase 1, Phase 2 through to Phase 3 efficacy studies and including Phase 4 registered as ...

South-East Asia is quickly growing in number of reported clinical trials and was the only region not to see a decrease since the peak of trials during the COVID-19 pandemic, driven largely by trials in India (90% of trials; select South-East Asia 2023 in Chart A and hover of India in chart C).

It also includes some clinical trials conducted outside the EU/EEA or some older trials that meet certain criteria. Study records indicate the trial protocol and provide results where available. Records can be searched using an advanced search function. Currently, the registry displays over 34,000 clinical trials. Pan African Clinical Trial ...