Myasthenia Gravis Prognosis - Rare Disease Advisor
Myasthenia gravis (MG) is a rare autoimmune disease in which the body attacks components of the neuromuscular junction (NMJ), causing weakness of voluntary skeletal muscles and fatigue with repetitive movements. MG especially affects the eyes, peripheral extremities, bulbar system, and respiratory system. 1 General Prognosis. In general, most individuals with MG who receive the appropriate ...
Primary Biliary Cholangitis Life Expectancy - Rare Disease Advisor
Primary biliary cholangitis (PBC) is a chronic cholestatic and autoimmune liver disease that mainly affects middle-aged women. PBC is caused by a combination of genetic and environmental factors and is characterized by the destruction of the intrahepatic bile ducts.
Muscular Dystrophy History - Rare Disease Advisor
The first person to report on muscular dystrophy was Sir Charles Bell, a Scottish surgeon, anatomist, physiologist, and neurologist, who wrote an essay in 1830 about a disease that led to progressive muscle weakness in boys. 1 . Six years later, 2 Italian physicians, Giovanni Semmola and Gaetano Conte, wrote about 2 brothers who had symptoms of generalized weakness.
Rare Disease News, Perspectives & Resources - Rare Disease Advisor
Rare Disease News is the premier online resource for the latest rare disease news, perspectives and information.
ANCA-Associated Vasculitis (AAV) - Rare Disease Advisor
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a group of 3 diseases: granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). 1. The clinical features of AAV are closely related to its underlying pathophysiologic mechanisms.
Systemic Sclerosis Diet and Nutrition - Rare Disease Advisor
Systemic sclerosis (SSc) is a rare autoimmune-mediated connective tissue disorder that causes fibrosis and microvascular damage throughout multiple systems, including the skin, joints, and internal organs. Dietary and nutritional interventions are essential for patients with SSc due to gastrointestinal (GI) complications that can impair food intake, nutrient absorption, and …
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare, acquired, immune-mediated neurological disease characterized by inflammation of peripheral nerves and nerve roots with destruction of the myelin sheath, which is the fatty protective covering of the nerve fibers. This demyelination results in typical symmetrical motor and sensory weakness. 1 Both sexes can develop CIDP at any ...
Immune Thrombocytopenia Life Expectancy - Rare Disease Advisor
Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by an abnormal decrease in platelet count. It is caused by a dysfunctional immune system that leads to a decrease in platelet survival and production. 1 Life Expectancy Factors
Spinal Muscular Atrophy Prognosis - Rare Disease Advisor
Prognosis by SMA Disease Type. Spinal muscular atrophy (SMA) can severely affect a patient’s life expectancy. The prognosis depends on the SMA type that has been diagnosed. For example, life expectancy for 95% of patients with the most common type of SMA, type 1, is less than 18 months. 1 The life expectancy of those with the adult-onset form of the disease, SMA type 4, is no different from ...
Muscular Dystrophy Prognosis - Rare Disease Advisor
Muscular dystrophy (MD) prognosis varies depending on the type of disease a patient has. There are many types of MD caused by mutations in various genes.